BDBM50533353 CHEMBL4549947

SMILES Cc1ccc(cc1)-c1ccc(Nc2cc(=O)n(O)c(=O)[nH]2)cc1

InChI Key InChIKey=GZWREPINEZUJGH-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50533353   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50533353(CHEMBL4549947)
Affinity DataIC50:  700nMAssay Description:Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in DNA 3'-end cleavage using HTS2 substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50533353(CHEMBL4549947)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibition of polymerase activity of HIV1 reverse transcriptase using poly(rA)-oligo(dT)16 and [3H]-TTP incubated for 20 mins by liquid scintillation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50533353(CHEMBL4549947)
Affinity DataIC50:  500nMAssay Description:Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in RNA 5'-end directed cleavage using HTS3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50533353(CHEMBL4549947)
Affinity DataIC50:  400nMAssay Description:Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in nonspecific internal cleavage using HTS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50533353(CHEMBL4549947)
Affinity DataIC50:  400nMAssay Description:Inhibition of re-constituted HIV1 reverse transcriptase RNase H domain fragmentMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50533353(CHEMBL4549947)
Affinity DataIC50:  9.30E+4nMAssay Description:Inhibition of HIV integrase pre-incubated for 10 mins before addition of oligo-5'-biotin ATGTGGAAAATCTCTAGCA annealed with ACTGCTAGAGATTTTCCACAT 3'-C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed