BDBM50536666 CHEMBL4588797
SMILES N[C@@H](CCSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cc(C#N)c2c(N)ncnc12)C(O)=O
InChI Key InChIKey=XLTWYAYAFLGUEQ-OPYVMVOTSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50536666
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of DOT1L (unknown origin) using chicken nucleosome as substrate in presence of [3H]SAM incubated for 1 hr by TopCount methodMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 3(Homo sapiens)
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 870nMAssay Description:Inhibition of PRMT3 (unknown origin)More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of PRMT5 (unknown origin)More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant DOT1L (1 to 420 amino acids) expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of DNMT1 (unknown origin)More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
University College London
Curated by ChEMBL
University College London
Curated by ChEMBL
Affinity DataIC50: 9.90E+4nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair