BDBM50536837 CHEMBL4572200

SMILES FCC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1

InChI Key InChIKey=QRHGYABXBVODEX-SFHVURJKSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50536837   

TargetCysteine protease ATG4B(Homo sapiens (Human))
Roche Pharma Research And Early Development

Curated by ChEMBL
LigandPNGBDBM50536837(CHEMBL4572200)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of full length N-terminal His6-tagged ATG4B (unknown origin) expressed in Escherichia coli BL21(DE3) cells using His-GATE-16-GST as substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease ATG4B(Homo sapiens (Human))
Roche Pharma Research And Early Development

Curated by ChEMBL
LigandPNGBDBM50536837(CHEMBL4572200)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of ATG4B (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCysteine protease ATG4B(Homo sapiens (Human))
Roche Pharma Research And Early Development

Curated by ChEMBL
LigandPNGBDBM50536837(CHEMBL4572200)
Affinity DataIC50:  1.47E+3nMAssay Description:Inhibition of ATG4B (unknown origin) expressed in HEK293T cells coexpressing HTRA4 and Actin-LC3B-dNGLuc after 24 hrs by luciferase release assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease ATG4B(Homo sapiens (Human))
Roche Pharma Research And Early Development

Curated by ChEMBL
LigandPNGBDBM50536837(CHEMBL4572200)
Affinity DataIC50:  1.13E+3nMAssay Description:Inhibition of ATG4B (unknown origin) using His-GATE-16-GST as substrate preincubated for 30 mins followed by substrate addition measured after 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed