BDBM50536857 CHEMBL4581663

SMILES FCC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)c1cccc2c(F)cccc12

InChI Key InChIKey=NYBBKZPDXHQHTJ-NRFANRHFSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50536857   

TargetCysteine protease ATG4B(Homo sapiens (Human))
Roche Pharma Research And Early Development

Curated by ChEMBL
LigandPNGBDBM50536857(CHEMBL4581663)
Affinity DataIC50:  15nMAssay Description:Inhibition of ATG4B (unknown origin) expressed in HEK293T cells coexpressing HTRA4 and Actin-LC3B-dNGLuc after 24 hrs by luciferase release assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease ATG4B(Homo sapiens (Human))
Roche Pharma Research And Early Development

Curated by ChEMBL
LigandPNGBDBM50536857(CHEMBL4581663)
Affinity DataIC50: <100nMAssay Description:Inhibition of ATG4B (unknown origin) using FRETGATE-16 as substrate incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCysteine protease ATG4B(Homo sapiens (Human))
Roche Pharma Research And Early Development

Curated by ChEMBL
LigandPNGBDBM50536857(CHEMBL4581663)
Affinity DataIC50:  57nMAssay Description:Inhibition of ATG4B (unknown origin) using His-GATE-16-GST as substrate preincubated for 30 mins followed by substrate addition measured after 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed