BDBM50537592 CHEMBL4632881

SMILES C1CN(CCN1c1cc(-c2ccncc2)c(nn1)-c1ccccc1)c1ncccn1

InChI Key InChIKey=OAXXZZBGZDNSGE-UHFFFAOYSA-N

Data  2 KI  8 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50537592   

TargetCasein kinase I isoform delta(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50537592(CHEMBL4632881)
Affinity DataKi:  40nMAssay Description:Inhibitory activity against HIV-1 Y181C reverse transcriptase.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50537592(CHEMBL4632881)
Affinity DataKi:  620nMAssay Description:Inhibitory activity against HIV-1 Mutant Reverse transcriptase K103NMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50537592(CHEMBL4632881)
Affinity DataIC50: <1.00E+3nMAssay Description:Concentration required to inhibit the phosphorylation of a 14-residue fragment of phospholipase C gamma 1 by Epidermal growth factor receptor from A4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50537592(CHEMBL4632881)
Affinity DataIC50: <1.00E+3nMAssay Description:Concentration required to inhibit the phosphorylation of a 14-residue fragment of phospholipase C gamma 1 by Epidermal growth factor receptor from A4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50537592(CHEMBL4632881)
Affinity DataIC50:  230nMAssay Description:Inhibitory activity against HIV-1 Y181C reverse transcriptase.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50537592(CHEMBL4632881)
Affinity DataIC50:  600nMAssay Description:Inhibitory activity against HIV-1 Y181C reverse transcriptase.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMitogen-activated protein kinase 11(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50537592(CHEMBL4632881)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against HIV-1 Mutant Reverse transcriptase K103NMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50537592(CHEMBL4632881)
Affinity DataIC50: <1.00E+3nMAssay Description:Concentration required to inhibit the phosphorylation of a 14-residue fragment of phospholipase C gamma 1 by Epidermal growth factor receptor from A4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetTRAF2 and NCK-interacting protein kinase(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50537592(CHEMBL4632881)
Affinity DataIC50: <1.00E+3nMAssay Description:Concentration required to inhibit the phosphorylation of a 14-residue fragment of phospholipase C gamma 1 by Epidermal growth factor receptor from A4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D3(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50537592(CHEMBL4632881)
Affinity DataIC50: <1.00E+3nMAssay Description:Concentration required to inhibit the phosphorylation of a 14-residue fragment of phospholipase C gamma 1 by Epidermal growth factor receptor from A4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed