BDBM50539686 CHEMBL4644587

SMILES CCOc1cc(Cl)c(cc1N1CCOCC1)-c1ncc(-c2nc3ccccc3s2)c(=O)[nH]1

InChI Key InChIKey=NVCVBDIRCUPQJE-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50539686   

TargetHydroxycarboxylic acid receptor 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50539686(CHEMBL4644587)
Affinity DataEC50:  490nMAssay Description:Agonist activity at human GPR81 overexpressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50539686(CHEMBL4644587)
Affinity DataEC50: >2.20E+4nMAssay Description:Agonist activity at human GPR109A receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50539686(CHEMBL4644587)
Affinity DataIC50:  5.20E+3nMAssay Description:Displacement of [125I]-ghrelin from human GHS-R1a stably expressed in HEK cell membrane measured after 60 mins by gamma counter methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed