BDBM50539693 CHEMBL4646005

SMILES CCOc1cc(Cl)c(cc1N1CCOCC1)C(=O)Nc1nc2ccc(OC3CCN(C)CC3)cc2s1

InChI Key InChIKey=GOWIGCYUKIGMHY-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50539693   

TargetHydroxycarboxylic acid receptor 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50539693(CHEMBL4646005)
Affinity DataEC50:  110nMAssay Description:Agonist activity at human GPR81 overexpressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50539693(CHEMBL4646005)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at human GPR109A receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50539693(CHEMBL4646005)
Affinity DataIC50: >3.00E+4nMAssay Description:Displacement of [125I]-ghrelin from human GHS-R1a stably expressed in HEK cell membrane measured after 60 mins by gamma counter methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed