BDBM50540286 CHEMBL4636550

SMILES Cc1cc(Br)c(NC2=NCCN2)c2ccccc12

InChI Key InChIKey=UYAOIRISFNRFCT-UHFFFAOYSA-N

Data  4 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50540286   

TargetComplement factor B(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50540286(CHEMBL4636550)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of human serine protease factor B catalytic domain (D470 to L764 residues) assessed as inhibition of cleavage cobra venom factor (CVF):Bb ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetComplement factor B(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50540286(CHEMBL4636550)
Affinity DataKd:  1.00E+4nMAssay Description:Binding affinity to human serine protease factor B by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50540286(CHEMBL4636550)
Affinity DataIC50:  180nMAssay Description:Inhibition of adrenergic receptor alpha2c (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50540286(CHEMBL4636550)
Affinity DataIC50:  300nMAssay Description:Inhibition of adrenergic receptor alpha1a (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50540286(CHEMBL4636550)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of human ERG by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed