BDBM50540399 CHEMBL4646175::US11427590, Entry 60

SMILES COc1ccc(cc1OC)-c1c(C)nc2c(cc(C)nn12)N1CC[C@H](C1)OC(C)=O

InChI Key InChIKey=AGOWEAGKNXQMFP-QGZVFWFLSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50540399   

TargetSphingomyelin phosphodiesterase 3(Homo sapiens)
The Johns Hopkins University

US Patent
LigandPNGBDBM50540399(CHEMBL4646175 | US11427590, Entry 60)
Affinity DataIC50:  400nMAssay Description:The fluorescence based assay to monitor the activity of human nSMase2 in the presence or absence of potential inhibitors has been described recently....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingomyelin phosphodiesterase 3(Homo sapiens)
The Johns Hopkins University

US Patent
LigandPNGBDBM50540399(CHEMBL4646175 | US11427590, Entry 60)
Affinity DataIC50:  400nMAssay Description:Inhibition of human recombinant full-length nSMase expressed in HEK293 cells using sphingomyelin as substrate measured after 1 hr by alkaline phospha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed