BDBM50540938 CHEMBL4644738

SMILES NS(=O)(=O)c1ccc(CCN(Cc2ccc(F)cc2)C(=O)CN(CCC#N)CCc2ccccc2)cc1

InChI Key InChIKey=YBIJNZHHAMTRHM-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50540938   

TargetCarbonic anhydrase 12(Homo sapiens (Human))
University Of Firenze

Curated by ChEMBL
LigandPNGBDBM50540938(CHEMBL4644738)
Affinity DataKi:  9.80nMAssay Description:Inhibition of human CA12 preincubated for 15 mins by stopped-flow CO2 hydration kinetic assay based Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Firenze

Curated by ChEMBL
LigandPNGBDBM50540938(CHEMBL4644738)
Affinity DataKi:  133nMAssay Description:Inhibition of human CA2 preincubated for 15 mins by stopped-flow CO2 hydration kinetic assay based Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
University Of Firenze

Curated by ChEMBL
LigandPNGBDBM50540938(CHEMBL4644738)
Affinity DataKi:  676nMAssay Description:Inhibition of human CA1 preincubated for 15 mins by stopped-flow CO2 hydration kinetic assay based Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
University Of Firenze

Curated by ChEMBL
LigandPNGBDBM50540938(CHEMBL4644738)
Affinity DataKi:  4.13E+3nMAssay Description:Inhibition of human CA4 preincubated for 15 mins by stopped-flow CO2 hydration kinetic assay based Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed