BDBM50544020 CHEMBL4638213

SMILES CC(C)c1onc(c1COc1ccc(cc1)-c1nc2ccc(cc2n1CC1CCCCC1)C(O)=O)-c1c(Cl)cccc1Cl

InChI Key InChIKey=CPLLKGZGVGEJKT-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50544020   

TargetBile acid receptor(Homo sapiens (Human))
Hiroshima International University

Curated by ChEMBL
LigandPNGBDBM50544020(CHEMBL4638213)
Affinity DataEC50:  20nMAssay Description:Agonist activity at GST-fused FXR-LBD (unknown origin) incubated with Fluorecein-SRC2-2 coactivator peptide as substrate by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Hiroshima International University

Curated by ChEMBL
LigandPNGBDBM50544020(CHEMBL4638213)
Affinity DataIC50:  346nMAssay Description:Antagonist activity at human VDR transfected in HEK293T cells measured after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Hiroshima International University

Curated by ChEMBL
LigandPNGBDBM50544020(CHEMBL4638213)
Affinity DataEC50:  0.520nMAssay Description:Agonist activity at human FXR expressed in human HuH7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed