BDBM50545966 CHEMBL4795297

SMILES COc1ccc(Cl)cc1-c1nn(C)cc1NC(=O)c1cncc2cccnc12

InChI Key InChIKey=CKZVAGSZXQDMER-UHFFFAOYSA-N

Data  2 KI  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50545966   

TargetNon-receptor tyrosine-protein kinase TYK2/Tyrosine-protein kinase JAK1/Tyrosine-protein kinase JAK2/Tyrosine-protein kinase JAK3(Homo sapiens (Human))
Genentech

Curated by ChEMBL

LigandBDBM50545966(CHEMBL4795297)Copy SMILESCopy InChI

Affinity DataIC50:  38nMAssay Description:Inhibition of JAK in human BEAS-2B cells assessed as reduction in IL13-induced STAT6 phosphorylation incubated for 1 hr followed by IL13 addition and...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
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Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
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