BDBM50547628 CHEMBL4753603

SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc(C#CC#Cc2cnc([nH]2)[C@@H]2CCCN2C(=O)[C@H](NC(=O)OC)c2ccccc2)c(c1)-c1cccc(F)c1F

InChI Key InChIKey=OGEVUVDERZAKRB-GZPQCZOQSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50547628   

TargetNonstructural protein 5A(Hepatitis C virus)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50547628(CHEMBL4753603)
Affinity DataIC50:  0.0190nMAssay Description:Inhibition of HCV genotype 5a NS5A infected in Huh7 cells assessed as reduction in viral replication incubated 3 days and measured by bright Glo-luci...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50547628(CHEMBL4753603)
Affinity DataIC50:  0.0160nMAssay Description:Inhibition of HCV genotype 3a NS5A infected in Huh7 cells assessed as reduction in viral replication incubated 3 days and measured by bright Glo-luci...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50547628(CHEMBL4753603)
Affinity DataIC50:  0.00100nMAssay Description:Inhibition of HCV genotype 2a NS5A infected in Huh7 cells assessed as reduction in viral replication incubated 3 days and measured by bright Glo-luci...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50547628(CHEMBL4753603)
Affinity DataIC50:  0.0280nMAssay Description:Inhibition of HCV genotype 1a NS5A infected in Huh7 cells assessed as reduction in viral replication incubated 3 days and measured by bright Glo-luci...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50547628(CHEMBL4753603)
Affinity DataIC50:  0.00300nMAssay Description:Inhibition of HCV genotype 1b NS5A infected in Huh7 cells assessed as reduction in viral replication incubated 3 days and measured by Celltiter Glo a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50547628(CHEMBL4753603)
Affinity DataIC50:  0.00600nMAssay Description:Inhibition of HCV genotype 4a NS5A infected in Huh7 cells assessed as reduction in viral replication incubated 3 days and measured by bright Glo-luci...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed