BDBM50547871 CHEMBL4757194
SMILES COCCN(C)[C@H]1CC[C@@H](CC1)Nc1ncc2cc(-c3ccc(NS(=O)(=O)Cc4ccc(F)cc4)c(F)c3)c(=O)n(C(C)C)c2n1
InChI Key InChIKey=JBQNRMBKELRISE-MCZWQBSQSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50547871
TargetSerine/threonine-protein kinase/endoribonuclease IRE1(Homo sapiens (Human))
Smith, Gambrell & Russell
Curated by ChEMBL
Smith, Gambrell & Russell
Curated by ChEMBL
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of human His-tagged IRE1alpha expressed in Sf9 insect cells preincubated for 1 hr followed by Alexa fluor 647-labeled probe addition and m...More data for this Ligand-Target Pair