BDBM50549456 CHEMBL4778736

SMILES Cc1cccc(Cc2nc3cc(O[C@H]4CC[C@H](CC4)C(O)=O)ccc3n2C)c1

InChI Key InChIKey=OJYFETIOPQLONV-HDICACEKSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50549456   

TargetCytochrome P450 2D6(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandPNGBDBM50549456(CHEMBL4778736)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandPNGBDBM50549456(CHEMBL4778736)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandPNGBDBM50549456(CHEMBL4778736)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandPNGBDBM50549456(CHEMBL4778736)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandPNGBDBM50549456(CHEMBL4778736)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLong-chain-fatty-acid--CoA ligase 1(Homo sapiens)
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandPNGBDBM50549456(CHEMBL4778736)
Affinity DataIC50:  42nMAssay Description:Inhibition of recombinant human ACSL1 assessed as reduction in acetyl-coA prodution incubated for 90 mins in presence of Coenzyme A, ATP and MgCl2 by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLong-chain-fatty-acid--CoA ligase 4(Homo sapiens)
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandPNGBDBM50549456(CHEMBL4778736)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of recombinant human ACSL4 assessed as reduction in acetyl-coA prodution incubated for 120 mins in presence of Coenzyme A, ATP and MgCl2 b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLong-chain-fatty-acid--CoA ligase 5(Homo sapiens)
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandPNGBDBM50549456(CHEMBL4778736)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of recombinant human ACSL5 assessed as reduction in acetyl-coA prodution incubated for 90 mins in presence of Coenzyme A, ATP and MgCl2 by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFatty acid CoA ligase Acsl3(Homo sapiens)
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandPNGBDBM50549456(CHEMBL4778736)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of recombinant human ACSL3 assessed as reduction in acetyl-coA prodution incubated for 90 mins in presence of Coenzyme A, ATP and MgCl2 by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLong-chain-fatty-acid--CoA ligase 1(Mus musculus)
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandPNGBDBM50549456(CHEMBL4778736)
Affinity DataIC50:  30nMAssay Description:Inhibition of recombinant mouse ACSL1 assessed as reduction in acetyl-coA prodution incubated for 90 mins in presence of Coenzyme A, ATP and MgCl2 by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLong-chain-fatty-acid--CoA ligase 6(Homo sapiens)
Shionogi Pharmaceutical Research Center

Curated by ChEMBL
LigandPNGBDBM50549456(CHEMBL4778736)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of recombinant human ACSL6 assessed as reduction in acetyl-coA prodution incubated for 60 mins in presence of Coenzyme A, ATP and MgCl2 by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed