BDBM50550026 CHEMBL4786690
SMILES [H][C@]1(CC[C@@H](CC1)c1ccnc2ccc(F)cc12)[C@@H](C)NC(=O)c1ccc(Cl)cc1
InChI Key InChIKey=AOJCHFNHRLPISK-ZACQAIPSSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 16 hits for monomerid = 50550026
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
Bristol Myers Squibb Research And Development
Curated by ChEMBL
Bristol Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of alpha1 nAChR (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: <50nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol Myers Squibb Research And Development
Curated by ChEMBL
Bristol Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataEC50: >5.00E+4nMAssay Description:Transactivation of PXR (unknown origin)More data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Bristol Myers Squibb Research And Development
Curated by ChEMBL
Bristol Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataIC50: 3.37E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
TargetCytochrome P450 4B1(Homo sapiens)
Bristol Myers Squibb Research And Development
Curated by ChEMBL
Bristol Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of human CYP450More data for this Ligand-Target Pair
TargetCytochrome P450 2C8(Homo sapiens (Human))
Bristol Myers Squibb Research And Development
Curated by ChEMBL
Bristol Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of human CYP2C8More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Bristol Myers Squibb Research And Development
Curated by ChEMBL
Bristol Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataIC50: 740nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of IDO1 in IFNgamma/LPS-stimulated human whole blood preincubated for 4 hrs followed by IFNgamma/LPS stimulation and incubated for 18 hrs ...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Bristol Myers Squibb Research And Development
Curated by ChEMBL
Bristol Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated mouse M109 cells preincubated for 2 hrs followed by IFNgamma stimulation and measured after 18 hrs byMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells preincubated for 2 hrs followed by IFNgamma stimulation and measured after 18 hrs byMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells preincubated for 2 hrs followed by recombinant human IFNgamma stimulation and measured aft...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Bristol Myers Squibb Research And Development
Curated by ChEMBL
Bristol Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated mouse M109 cells preincubated for 2 hrs followed by recombinant murine IFNgamma stimulation and measured af...More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Bristol Myers Squibb Research And Development
Curated by ChEMBL
Bristol Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataIC50: 740nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
TargetCytochrome P450 2C8(Homo sapiens (Human))
Bristol Myers Squibb Research And Development
Curated by ChEMBL
Bristol Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of human CYP2C8More data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Bristol Myers Squibb Research And Development
Curated by ChEMBL
Bristol Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataIC50: 3.37E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Bristol Myers Squibb Research And Development
Curated by ChEMBL
Bristol Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataIC50: >6.00E+3nMAssay Description:Inhibition of alpha7 nAChR (unknown origin)More data for this Ligand-Target Pair