BDBM50551188 CHEMBL4778826

SMILES COc1ccc(\C=C\C(=O)c2nnn(c2C)-c2ccc(Cl)cc2)cc1OC

InChI Key InChIKey=YOJHPSLHBFFDDL-ONNFQVAWSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50551188   

TargetHistone deacetylase 1(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50551188(CHEMBL4778826)
Affinity DataIC50:  1.53E+3nMAssay Description:Inhibition of HDAC1 in human RPMI-8226 cells incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50551188(CHEMBL4778826)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of HDAC2 in human RPMI-8226 cells incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50551188(CHEMBL4778826)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of HDAC3 in human RPMI-8226 cells incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50551188(CHEMBL4778826)
Affinity DataIC50:  388nMAssay Description:Inhibition of VEGFR2 in human RPMI-8226 cells incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50551188(CHEMBL4778826)
Affinity DataIC50:  9.99E+5nMAssay Description:Inhibition of HDAC6 in human RPMI-8226 cells incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor p65(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50551188(CHEMBL4778826)
Affinity DataIC50:  134nMAssay Description:Inhibition of NFkappaB p65 in human RPMI-8226 cells incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50551188(CHEMBL4778826)
Affinity DataIC50:  36nMAssay Description:Inhibition of EGFR in human RPMI-8226 cells incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50551188(CHEMBL4778826)
Affinity DataIC50:  47nMAssay Description:Inhibition of HDAC8 in human RPMI-8226 cells incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed