BDBM50552330 CHEMBL4745982

SMILES Cc1ccoc1C(=O)Nc1cc(C)c(cc1F)N1C(=O)c2ccccc2C1=O

InChI Key InChIKey=WMBNMWWQJFWLEY-UHFFFAOYSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50552330   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50552330(CHEMBL4745982)
Affinity DataEC50:  2.10E+3nMAssay Description:Positive allosteric modulation of mGluR5 (unknown origin) by calcium mobilization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50552330(CHEMBL4745982)
Affinity DataEC50:  74nMAssay Description:Positive allosteric modulation of human mGluR1 in presence of EC20 concentration of glutamate by calcium mobilization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 8(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50552330(CHEMBL4745982)
Affinity DataEC50:  189nMAssay Description:Positive allosteric modulation of mGluR8 (unknown origin) by calcium mobilization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50552330(CHEMBL4745982)
Affinity DataEC50:  180nMAssay Description:Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50552330(CHEMBL4745982)
Affinity DataEC50:  128nMAssay Description:Positive allosteric modulation of human mGluR4 by calcium mobilization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed