BDBM50552483 CHEMBL4763594

SMILES Nc1ccc(cc1)-c1cn(Cc2cc(cc(c2)-c2cccc(c2)C(O)=O)C(O)=O)nn1

InChI Key InChIKey=ZBQJXILHBDHMAS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50552483   

TargetUbiquitin carboxyl-terminal hydrolase isozyme L5(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50552483(CHEMBL4763594)
Affinity DataIC50:  3.29E+4nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human UCHL5 expressed in Escherichia coli BL21 (DE3) codon cells assessed as reduction in cleavage o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50552483(CHEMBL4763594)
Affinity DataIC50:  7.40E+4nMAssay Description:Inhibition of recombinant human UCHL3 assessed as reduction in cleavage of Ubiquitin-Rhodamine110-glycine to Ubiquitin and Rhodamine110-glycine using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50552483(CHEMBL4763594)
Affinity DataIC50:  9.20E+4nMAssay Description:Inhibition of recombinant human N-terminal MET and His6-tagged UCHL1 (Gln2 to Ala223 residues) expressed in Escherichia coli assessed as reduction in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed