BDBM50552678 CHEMBL4759036

SMILES CC(C)(C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)Cc1ccc(CNC(N)=N)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCc1ccc(cc1)C(N)=N

InChI Key InChIKey=HXVPWVPTVOOCMV-UNCTUWKVSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50552678   

TargetFurin(Homo sapiens (Human))
Philipps University

Curated by ChEMBL
LigandPNGBDBM50552678(CHEMBL4759036)
Affinity DataKi:  0.00500nMAssay Description:Inhibition of recombinant soluble human furin using Phac-Arg-Val-Arg-Arg-AMC fluorogenic substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFurin(Homo sapiens (Human))
Philipps University

Curated by ChEMBL
LigandPNGBDBM50552678(CHEMBL4759036)
Affinity DataKi:  0.00500nMAssay Description:Inhibition of human furin expressed in HEK293 cells using pGlu-Arg-Thr-LysArg-AMC as substrate and measured by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFurin(Homo sapiens (Human))
Philipps University

Curated by ChEMBL
LigandPNGBDBM50552678(CHEMBL4759036)
Affinity DataKi:  5.5nMAssay Description:Inhibition of recombinant soluble human furin using Phac-Arg-Val-Arg-Arg-AMC as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Philipps University

Curated by ChEMBL
LigandPNGBDBM50552678(CHEMBL4759036)
Affinity DataKi: >3.00E+3nMAssay Description:Inhibition pf human plasmin using Mes-Darg-Phe-Arg-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProthrombin(Bos taurus (Bovine))
Philipps University

Curated by ChEMBL
LigandPNGBDBM50552678(CHEMBL4759036)
Affinity DataKi: >3.00E+3nMAssay Description:Inhibition of bovine thrombin using Tos-Gly-Pro-Arg-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Philipps University

Curated by ChEMBL
LigandPNGBDBM50552678(CHEMBL4759036)
Affinity DataKi: >3.00E+3nMAssay Description:Inhibition of human factor Xa using Mes-Darg-Pro-Arg-AMC as flurogenic substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed