BDBM50553050 CHEMBL4744916

SMILES NCCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)Cc1cccc2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O

InChI Key InChIKey=ZEDRJAYWKIOVIG-HJOGWXRNSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50553050   

TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Homo sapiens)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50553050(CHEMBL4744916)
Affinity DataIC50:  1.00E+6nMAssay Description:Inhibition of NTMT1 in human HCT116 cells assessed as decrease in me3-SPK level incubated for 3 days by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Homo sapiens)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50553050(CHEMBL4744916)
Affinity DataIC50:  100nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL using GPKRIA p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed