BDBM50553830 CHEMBL4760981

SMILES COc1ccc(cc1)-n1nnc2cnc(N[C@@H]3CC[C@@H](N)C3)cc12

InChI Key InChIKey=JWYCUNYGNQEQHR-VXGBXAGGSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50553830   

TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50553830(CHEMBL4760981)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of recombinant His6-GST fusion tagged ERK3 (1 to 365 residues) (unknown origin) expressed in Sf21 insect cells using MK5 K51A mutant as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50553830(CHEMBL4760981)
Affinity DataIC50:  1.35E+4nMAssay Description:Inhibition of ERK3 (unknown origin) expressed in HEK293 cells cotransfected with nano-luciferase by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50553830(CHEMBL4760981)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of recombinant full length His6-GST fusion tagged ERK3 (1 to 721 residues) (unknown origin) using MK5 K51A mutant as substrate by ADP-Glo ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 6(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50553830(CHEMBL4760981)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of recombinant His6-GST fusion tagged ERK3 (1 to 471 residues) (unknown origin) expressed in Sf21 insect cells using MK5 K51A mutant as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed