BDBM50555397 CHEMBL4741023
SMILES Fc1cccc(c1)-c1cnc(Nc2cnc(cn2)C#N)cc1NC[C@H]1CNCCO1
InChI Key InChIKey=ICHCXQHWTRNWIJ-QGZVFWFLSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50555397
Affinity DataIC50: 6.40nMAssay Description:Inhibition of CHK1 (unknown origin) using 5-FAM-KKKVSRSGLYRSPSMPENLNRPR-COOH peptide as substrate incubated for 1 hr in presence of ATP by caliper mi...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sareum
Curated by ChEMBL
Sareum
Curated by ChEMBL
Affinity DataIC50: 8.80E+3nMAssay Description:Displacement of [3H]astemizole from human ERG expressed in HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of CHK1 in human HT-29 cells assessed as abrogation of etoposide-induced G2 checkpoint arrest by ELISAMore data for this Ligand-Target Pair