BDBM50555405 CHEMBL4784718
SMILES OC1(CCCC1)C#Cc1cnc(Nc2cnc(cn2)C#N)cc1NC[C@@H]1CNCCO1
InChI Key InChIKey=OGFJKRMWBHUEJX-SFHVURJKSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50555405
Affinity DataIC50: 2.10nMAssay Description:Inhibition of CHK1 (unknown origin) using 5-FAM-KKKVSRSGLYRSPSMPENLNRPR-COOH peptide as substrate incubated for 1 hr in presence of ATP by caliper mi...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sareum
Curated by ChEMBL
Sareum
Curated by ChEMBL
Affinity DataIC50: 1.60E+4nMAssay Description:Displacement of [3H]astemizole from human ERG expressed in HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 72nMAssay Description:Inhibition of CHK1 in human HT-29 cells assessed as abrogation of etoposide-induced G2 checkpoint arrest by ELISAMore data for this Ligand-Target Pair