BDBM50556037 CHEMBL4744163

SMILES CN1[C@@H](C(C#N)=C(C)N(C1=O)c1cccc(c1)C(F)(F)F)c1ccc(cc1S(C)(=N)=O)C#N

InChI Key InChIKey=TWDVKGZGYDFGQK-SMAGUSHISA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50556037   

TargetNeutrophil elastase(Homo sapiens (Human))
Endotherm

Curated by ChEMBL
LigandPNGBDBM50556037(CHEMBL4744163)
Affinity DataIC50:  0.25nMAssay Description:Inhibition of human neutrophil elastase using MeOSuc-AAPV-AMC as substrate measured after 60 mins by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed