BDBM50556281 CHEMBL4790545

SMILES COc1ccc2cc(ccc2c1)C(=O)NCCC1CCN(Cc2ccccc2)CC1

InChI Key InChIKey=AIIWJMPOAUNFLG-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50556281   

TargetCholinesterase(Equus caballus (Horse))
Csir-India

Curated by ChEMBL
LigandPNGBDBM50556281(CHEMBL4790545)
Affinity DataKi:  150nMAssay Description:Mixed type inhibition of equine serum BChE assessed as decrease in Vmax and increase in Km using varying level of S-butyrylthiocholine iodide as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Csir-India

Curated by ChEMBL
LigandPNGBDBM50556281(CHEMBL4790545)
Affinity DataKi:  210nMAssay Description:Non-competitive inhibition of recombinant human AChE assessed as decrease in Vmax with constant Km using varying level of acetylthiocholine iodide as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Csir-India

Curated by ChEMBL
LigandPNGBDBM50556281(CHEMBL4790545)
Affinity DataIC50:  410nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured ever...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Csir-India

Curated by ChEMBL
LigandPNGBDBM50556281(CHEMBL4790545)
Affinity DataIC50:  170nMAssay Description:Inhibition of recombinant human AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Csir-India

Curated by ChEMBL
LigandPNGBDBM50556281(CHEMBL4790545)
Affinity DataIC50:  470nMAssay Description:Inhibition of equine serum BChE using S-butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed