BDBM50560065 CHEMBL4777235

SMILES NCCCC[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O

InChI Key InChIKey=SSQCJZTZJJXGCX-BALDRSJZSA-N

Data  7 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50560065   

TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Homo sapiens)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50560065(CHEMBL4777235)
Affinity DataIC50:  230nMAssay Description:Inhibition of recombinant human full-length His6-tagged NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL competent cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Homo sapiens)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50560065(CHEMBL4777235)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of recombinant human full-length His6-tagged NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL competent cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Homo sapiens)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50560065(CHEMBL4777235)
Affinity DataIC50:  700nMAssay Description:Inhibition of recombinant human full-length His6-tagged NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL competent cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Homo sapiens)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50560065(CHEMBL4777235)
Affinity DataIC50:  200nMAssay Description:Inhibition of recombinant human full-length His6-tagged NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL competent cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 2(Homo sapiens)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50560065(CHEMBL4777235)
Affinity DataKd:  3.40E+3nMAssay Description:Binding affinity to recombinant human full-length His6-tagged NTMT2 by ITC assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Homo sapiens)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50560065(CHEMBL4777235)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of recombinant human full-length His6-tagged NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL competent cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Homo sapiens)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50560065(CHEMBL4777235)
Affinity DataIC50:  700nMAssay Description:Inhibition of recombinant human full-length His6-tagged NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL competent cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Homo sapiens)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50560065(CHEMBL4777235)
Affinity DataKd:  600nMAssay Description:Binding affinity to recombinant human full-length His6-tagged NTMT1 (1 to 222 residues) by ITC assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Homo sapiens)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50560065(CHEMBL4777235)
Affinity DataIC50:  0nMAssay Description:Inhibition of recombinant human full-length His6-tagged NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL competent cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed