BDBM50560385 CHEMBL4759397

SMILES CC(C)n1cnnc1-c1cccc(NC(=O)C2CCCCO2)n1

InChI Key InChIKey=ZKCUEAJARGYWOA-UHFFFAOYSA-N

Data  13 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50560385   

TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Takeda Research In California

Curated by ChEMBL
LigandPNGBDBM50560385(CHEMBL4759397)
Affinity DataIC50:  270nMAssay Description:Inhibition of ASK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Takeda Research In California

Curated by ChEMBL
LigandPNGBDBM50560385(CHEMBL4759397)
Affinity DataIC50:  251nMAssay Description:Inhibition of ASK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Takeda Research In California

Curated by ChEMBL
LigandPNGBDBM50560385(CHEMBL4759397)
Affinity DataIC50: <2.00E+4nMAssay Description:Inhibition of p38 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Takeda Research In California

Curated by ChEMBL
LigandPNGBDBM50560385(CHEMBL4759397)
Affinity DataIC50: <2.00E+4nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Takeda Research In California

Curated by ChEMBL
LigandPNGBDBM50560385(CHEMBL4759397)
Affinity DataIC50: <2.00E+4nMAssay Description:Inhibition of HER4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Takeda Research In California

Curated by ChEMBL
LigandPNGBDBM50560385(CHEMBL4759397)
Affinity DataIC50: <2.00E+4nMAssay Description:Inhibition of MER (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Takeda Research In California

Curated by ChEMBL
LigandPNGBDBM50560385(CHEMBL4759397)
Affinity DataIC50: <2.00E+4nMAssay Description:Inhibition of PRKKA1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Takeda Research In California

Curated by ChEMBL
LigandPNGBDBM50560385(CHEMBL4759397)
Affinity DataIC50: <2.00E+4nMAssay Description:Inhibition of ROCK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Takeda Research In California

Curated by ChEMBL
LigandPNGBDBM50560385(CHEMBL4759397)
Affinity DataIC50: <2.00E+4nMAssay Description:Inhibition of ITK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Takeda Research In California

Curated by ChEMBL
LigandPNGBDBM50560385(CHEMBL4759397)
Affinity DataIC50: <2.00E+4nMAssay Description:Inhibition of ERBB4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 3(Homo sapiens (Human))
Takeda Research In California

Curated by ChEMBL
LigandPNGBDBM50560385(CHEMBL4759397)
Affinity DataIC50: <2.00E+4nMAssay Description:Inhibition of EPHA3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Takeda Research In California

Curated by ChEMBL
LigandPNGBDBM50560385(CHEMBL4759397)
Affinity DataIC50:  3.16E+3nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Takeda Research In California

Curated by ChEMBL
LigandPNGBDBM50560385(CHEMBL4759397)
Affinity DataIC50: <2.00E+4nMAssay Description:Inhibition of RET (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed