BDBM50560703 CHEMBL1349996

SMILES CCN1\C(Sc2ccc(OC)cc12)=C/C(C)=O

InChI Key InChIKey=BGVLELSCIHASRV-NTUHNPAUSA-N

Data  2 KI  15 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50560703   

TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50560703(CHEMBL1349996)
Affinity DataKi:  210nMAssay Description:Inhibition of full length wild type CLK1 (unknown origin) expressed in HEK293 cells incubated for 2 hrs followed by NanoBRET NanoGlo Substrate additi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK3(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50560703(CHEMBL1349996)
Affinity DataKi:  5.20E+3nMAssay Description:Inhibition of recombinant CLK3 (unknown origin) using Ac-ERMRPRKRQGSVdP(Sox)G-NH2 as substrate after 5 mins by Omnia Kinase AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50560703(CHEMBL1349996)
Affinity DataKd: <100nMAssay Description:Binding affinity to CLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50560703(CHEMBL1349996)
Affinity DataKd: <100nMAssay Description:Binding affinity to CLK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50560703(CHEMBL1349996)
Affinity DataKd: <100nMAssay Description:Binding affinity to CLK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK3(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50560703(CHEMBL1349996)
Affinity DataKd:  1.00E+3nMAssay Description:Binding affinity to CLK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50560703(CHEMBL1349996)
Affinity DataKd:  100nMAssay Description:Binding affinity to PIM1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50560703(CHEMBL1349996)
Affinity DataKd:  100nMAssay Description:Binding affinity to PIM3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform gamma-2(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50560703(CHEMBL1349996)
Affinity DataKd:  100nMAssay Description:Binding affinity to CSNK1G2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform gamma-3(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50560703(CHEMBL1349996)
Affinity DataKd:  100nMAssay Description:Binding affinity to CSNK1G3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50560703(CHEMBL1349996)
Affinity DataKd:  100nMAssay Description:Binding affinity to CSNK1D (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50560703(CHEMBL1349996)
Affinity DataKd:  100nMAssay Description:Binding affinity to CSNK1E (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 19(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50560703(CHEMBL1349996)
Affinity DataKd:  100nMAssay Description:Binding affinity to MAP3K19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50560703(CHEMBL1349996)
Affinity DataKd:  75nMAssay Description:Inhibition of CLK1 (H148 to I484 residues) (unknown origin) at 15 uM by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK3(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50560703(CHEMBL1349996)
Affinity DataKd:  7.78E+3nMAssay Description:Inhibition of CLK3 (R134 to T484 residues) (unknown origin) at 15 uM by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50560703(CHEMBL1349996)
Affinity DataKd:  100nMAssay Description:Binding affinity to DYRK1A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50560703(CHEMBL1349996)
Affinity DataKd:  100nMAssay Description:Binding affinity to DYRK1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed