BDBM50561775 CHEMBL4792696

SMILES CC(=O)Nc1ccc(NC(=O)Nc2nc(N3CCOCC3)c3ccccc3n2)cc1

InChI Key InChIKey=NAQIPIOFNXTKIE-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50561775   

TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Temple University

Curated by ChEMBL

LigandBDBM50561775(CHEMBL4792696)Copy SMILESCopy InChI

Affinity DataIC50:  114nMAssay Description:Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Temple University

Curated by ChEMBL

LigandBDBM50561775(CHEMBL4792696)Copy SMILESCopy InChI

Affinity DataIC50:  0.700nMAssay Description:Inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in pres...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI