BDBM50562606 CHEMBL4792256

SMILES CC(C)n1cc(C)c2c(cc(cc12)-c1ccc(cc1)N1CCNCC1)C(=O)NCc1c(C)cc(C)[nH]c1=O

InChI Key InChIKey=FIMUWTGRAKIIDX-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50562606   

TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50562606(CHEMBL4792256)
Affinity DataKi:  0.5nMAssay Description:Inhibition of human FLAG-tagged EZH2 using H3K27me as substrate in presence of [3H]-SAM incubated for 30 mins by Cheng-Prusoff analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed