BDBM50562873 CHEMBL4786296

SMILES CCOCCC[C@H]1CCc2cc(ccc2C1)[C@H]1CC[C@](N)(COP(O)(O)=O)C1

InChI Key InChIKey=VHKORLDZIRFKDI-ORYQWCPZSA-N

Data  1 IC50  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50562873   

TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Bristol Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM50562873(CHEMBL4786296)
Affinity DataEC50:  5.20nMAssay Description:Agonist activity at human recombinant S1P1 expressed in CHO cells assessed as stimulation of ERK phosphorylation incubated for 7 mins by microplate r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Bristol Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM50562873(CHEMBL4786296)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at recombinant human S1P3 expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding measured after 45 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 4(Homo sapiens (Human))
Bristol Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM50562873(CHEMBL4786296)
Affinity DataEC50:  10nMAssay Description:Agonist activity at recombinant human S1P4 expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding measured after 45 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Bristol Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM50562873(CHEMBL4786296)
Affinity DataEC50:  0.400nMAssay Description:Agonist activity at human recombinant C-terminal GFP-fused S1P1 expressed in CHO cells assessed as induction of receptor internalization incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Bristol Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM50562873(CHEMBL4786296)
Affinity DataIC50:  0.0400nMAssay Description:Displacement of [33P]-SIP from human recombinant S1P1 expressed in CHO cell membranes measured after 45 mins by TopCount scintillation counting metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Bristol Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM50562873(CHEMBL4786296)
Affinity DataEC50:  2.10nMAssay Description:Agonist activity at recombinant human S1P1 expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding measured after 45 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Bristol Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM50562873(CHEMBL4786296)
Affinity DataEC50:  4.90nMAssay Description:Agonist activity at recombinant human S1P5 expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding measured after 45 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed