BDBM50563534 CHEMBL4778153
SMILES CC(C)(C)c1ccc(cc1)-c1coc2ccc(nc12)-c1cn[nH]n1
InChI Key InChIKey=KTGZHJWTKLQHBK-UHFFFAOYSA-N
Data 21 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 21 hits for monomerid = 50563534
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CLK1 (unknown origin) by NanoBRET cellular target engagement assayMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CDKL3 (unknown origin) by NanoBRET cellular target engagement assayMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of human recombinant CLK2 using YRRAAVPPSPSLSR substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of human full length recombinant CLK3 using ERMRPRKRQGSVR substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of human recombinant CLK4 using YRRAAVPPSPSLS substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Masaryk University
Curated by ChEMBL
Masaryk University
Curated by ChEMBL
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of human full length recombinant DYRK1A using RRRFRPASPLRGPP substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Masaryk University
Curated by ChEMBL
Masaryk University
Curated by ChEMBL
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of human full length recombinant DYRK1B using RRRFRPASPLRGPP substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Masaryk University
Curated by ChEMBL
Masaryk University
Curated by ChEMBL
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of human full length recombinant DYRK2 using casein substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
TargetHomeodomain-interacting protein kinase 1(Homo sapiens (Human))
Masaryk University
Curated by ChEMBL
Masaryk University
Curated by ChEMBL
Affinity DataIC50: 285nMAssay Description:Inhibition of human recombinant HIPK1 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
TargetHomeodomain-interacting protein kinase 2(Homo sapiens (Human))
Masaryk University
Curated by ChEMBL
Masaryk University
Curated by ChEMBL
Affinity DataIC50: 123nMAssay Description:Inhibition of human recombinant HIPK2 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
TargetHomeodomain-interacting protein kinase 3(Homo sapiens (Human))
Masaryk University
Curated by ChEMBL
Masaryk University
Curated by ChEMBL
Affinity DataIC50: 283nMAssay Description:Inhibition of human recombinant HIPK3 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CLK2 (unknown origin) by NanoBRET cellular target engagement assayMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CLK3 (unknown origin) by NanoBRET cellular target engagement assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of CLK4 (unknown origin) by NanoBRET cellular target engagement assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Masaryk University
Curated by ChEMBL
Masaryk University
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of DYRK1A (unknown origin) by NanoBRET cellular target engagement assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Masaryk University
Curated by ChEMBL
Masaryk University
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of DYRK1B (unknown origin) by NanoBRET cellular target engagement assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Masaryk University
Curated by ChEMBL
Masaryk University
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of DYRK2 (unknown origin) by NanoBRET cellular target engagement assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 9(Homo sapiens (Human))
Masaryk University
Curated by ChEMBL
Masaryk University
Curated by ChEMBL
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of MLK1 (unknown origin) by NanoBRET cellular target engagement assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 10(Homo sapiens (Human))
Masaryk University
Curated by ChEMBL
Masaryk University
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of MLK2 (unknown origin) by NanoBRET cellular target engagement assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Masaryk University
Curated by ChEMBL
Masaryk University
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of MLK3 (unknown origin) by NanoBRET cellular target engagement assayMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of human recombinant CLK1 using ERMRPRKRQGSVR substrate by radiometric scintillation assayMore data for this Ligand-Target Pair