BDBM50563539 CHEMBL4762964
SMILES Cn1cc(cn1)-c1ccc2occ(-c3cccc(c3)-c3cc[nH]n3)c2n1
InChI Key InChIKey=MEZZCEDCBNWCRR-UHFFFAOYSA-N
Data 10 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50563539
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant CLK1 using ERMRPRKRQGSVR substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant CLK2 using YRRAAVPPSPSLSR substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.64E+3nMAssay Description:Inhibition of human full length recombinant CLK3 using ERMRPRKRQGSVR substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant CLK4 using YRRAAVPPSPSLS substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
TargetHomeodomain-interacting protein kinase 3(Homo sapiens (Human))
Masaryk University
Curated by ChEMBL
Masaryk University
Curated by ChEMBL
Affinity DataIC50: 128nMAssay Description:Inhibition of human recombinant HIPK3 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Masaryk University
Curated by ChEMBL
Masaryk University
Curated by ChEMBL
Affinity DataIC50: 1.89E+3nMAssay Description:Inhibition of human full length recombinant DYRK1B using RRRFRPASPLRGPP substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Masaryk University
Curated by ChEMBL
Masaryk University
Curated by ChEMBL
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of human full length recombinant DYRK2 using casein substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
TargetHomeodomain-interacting protein kinase 1(Homo sapiens (Human))
Masaryk University
Curated by ChEMBL
Masaryk University
Curated by ChEMBL
Affinity DataIC50: 125nMAssay Description:Inhibition of human recombinant HIPK1 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
TargetHomeodomain-interacting protein kinase 2(Homo sapiens (Human))
Masaryk University
Curated by ChEMBL
Masaryk University
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant HIPK2 using myelin substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Masaryk University
Curated by ChEMBL
Masaryk University
Curated by ChEMBL
Affinity DataIC50: 116nMAssay Description:Inhibition of human full length recombinant DYRK1A using RRRFRPASPLRGPP substrate by radiometric scintillation assayMore data for this Ligand-Target Pair