BDBM50564975 CHEMBL4784430

SMILES COc1cc(NS(C)(=O)=O)cc(c1)-c1cc(cnc1N)-c1ccc(cc1)N1CCNCC1

InChI Key InChIKey=WTNLXMJMLHJDKF-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50564975   

TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of Houston

Curated by ChEMBL
LigandPNGBDBM50564975(CHEMBL4784430)
Affinity DataIC50:  51nMAssay Description:Inhibition of recombinant human RIPK2 incubated for 2 hr by ADP-Glo assayMore data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Homo sapiens (Human))
University Of Houston

Curated by ChEMBL
LigandPNGBDBM50564975(CHEMBL4784430)
Affinity DataIC50:  390nMAssay Description:Inhibition of human NOD2 expressed in HEK293 cells coexpressing NFkappaB-SEAP reporter measured after 7 to 9 hrs by HEKBIue reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1(Homo sapiens (Human))
University Of Houston

Curated by ChEMBL
LigandPNGBDBM50564975(CHEMBL4784430)
Affinity DataIC50:  5nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of 10 uM [gamma33P] ATP by kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed