BDBM50565818 CHEMBL4776915

SMILES CC(=O)N[C@H](CCCN)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O

InChI Key InChIKey=YLVUKTHOPXMSDE-YAGLTGEFSA-N

Data  4 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50565818   

TargetMelanocortin receptor 4(Homo sapiens (Human))
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50565818(CHEMBL4776915)
Affinity DataKi:  0.0417nMAssay Description:Displacement of [125I]-[NIe,DPhe7]-alpha-MSH from human MC4R expressed in HEK293 cell membranes incubated for 120 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50565818(CHEMBL4776915)
Affinity DataKi:  0.0420nMAssay Description:Displacement of [125I]-[NIe,DPhe7]-alpha-MSH from human MC4R expressed in HEK293 cell membranes incubated for 120 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50565818(CHEMBL4776915)
Affinity DataKi:  3.70nMAssay Description:Displacement of [125I]-[NIe,DPhe7]-alpha-MSH from human MC3R expressed in HEK293 cell membranes incubated for 120 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50565818(CHEMBL4776915)
Affinity DataKi:  3.75nMAssay Description:Displacement of [125I]-[NIe,DPhe7]-alpha-MSH from human MC3R expressed in HEK293 cell membranes incubated for 120 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50565818(CHEMBL4776915)
Affinity DataIC50:  50nMAssay Description:Antagonist activity at human MC4R expressed in HEK293 cells expressing the GScAMP22F cAMP reporter assessed as reduction in alpha-MSH-induced cAMP ac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50565818(CHEMBL4776915)
Affinity DataIC50:  5.14E+3nMAssay Description:Antagonist activity at human MC3R expressed in HEK293 cells expressing the GScAMP22F cAMP reporter assessed as reduction in alpha-MSH-induced cAMP ac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50565818(CHEMBL4776915)
Affinity DataIC50:  5.13E+3nMAssay Description:Antagonist activity at human MC3R expressed in HEK293 cells expressing the GScAMP22F cAMP reporter assessed as reduction in alpha-MSH-induced cAMP ac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50565818(CHEMBL4776915)
Affinity DataIC50:  50nMAssay Description:Antagonist activity at human MC4R expressed in HEK293 cells expressing the GScAMP22F cAMP reporter assessed as reduction in alpha-MSH-induced cAMP ac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed