BDBM50566353 CHEMBL4862485

SMILES [H][C@]12C[C@H]([C@H](O)[C@@]1(O)CC[C@@H]2Cc1ccc2cc(F)c(N)nc2c1)n1ccc2c(C)ncnc12

InChI Key InChIKey=CKKZPYGYLPGVCZ-RDFICPIJSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50566353   

TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50566353(CHEMBL4862485)
Affinity DataEC50:  11nMAssay Description:Inhibition of PRMT5 (unknown origin) assessed as inhibition of symmetric dimethylation of arginine incubated for 3 days by fluorescence based cellula...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed