BDBM50568482 CHEMBL4858288
SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1nnn[nH]1)c1ccc(N(Cc2nnn[nH]2)S(=O)(=O)c2ccc(OC)cc2)c2ccccc12
InChI Key InChIKey=QUJAHTSGLDPGHW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50568482
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 97nMAssay Description:Inhibition of recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3)pLysS cells interaction with FITC-9m...More data for this Ligand-Target Pair
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
The State University Of New Jersey
Curated by ChEMBL
The State University Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3)pLysS cells interaction with FITC-9m...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of human Keap1-Nrf2 protein-protein interactionMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human Keap1-Nrf2 protein-protein interaction by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 40nMAssay Description:Binding affinity to human KEAP1 by isothermal titration calorimetric assayMore data for this Ligand-Target Pair