BDBM50568997 CHEMBL4853178

SMILES COc1ccc(CNC(=O)c2cnc3ccc(cn23)-c2ccc3ncccc3c2)cc1

InChI Key InChIKey=AAYFHKFUAWLHMY-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50568997   

TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50568997(CHEMBL4853178)
Affinity DataIC50:  4nMAssay Description:Inhibition of recombinant human CLK1 (130 to end residues) using ERMRPRKRQGSVR as substrate incubated for 40 mins in presence of [gamma-33ATP] by sci...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50568997(CHEMBL4853178)
Affinity DataIC50:  50nMAssay Description:Inhibition of recombinant human CLK2 (138 to end residues) using YRRAAVPPSPSLSRHSSPHQS(p)EDEEE as substrate incubated for 40 mins in presence of [gam...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50568997(CHEMBL4853178)
Affinity DataIC50:  148nMAssay Description:Inhibition of recombinant full length human DYRK1B using RRRFRPASPLRGPPK as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintilla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50568997(CHEMBL4853178)
Affinity DataIC50:  17nMAssay Description:Inhibition of recombinant human CLK4 (128 to end residues) using YRRAAVPPSPSLSRHSSPHQS(p)EDEEE as substrate incubated for 40 mins in presence of [gam...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50568997(CHEMBL4853178)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant full length human DYRK1A using RRRFRPASPLRGPPK as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintilla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK3(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50568997(CHEMBL4853178)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant full length human CLK3 using ERMRPRKRQGSVR as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintillation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed