BDBM50569675 CHEMBL4859773

SMILES COc1cc2CCN(C)Cc2cc1Nc1ncc(C(N)=O)c(Nc2c(F)cccc2CO)n1

InChI Key InChIKey=MTHVZJPLOFYJNG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50569675   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50569675(CHEMBL4859773)
Affinity DataIC50:  0.460nMAssay Description:Inhibition of HPK1 (unknown origin) using SLP76 as substrate incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed