BDBM50572198 CHEMBL4873479

SMILES COc1ccc2nccc(CCN3CCC(CC3)NCc3cc(F)c(Br)c(F)c3)c2n1

InChI Key InChIKey=RDTDFCZCBIXFEI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50572198   

TargetDNA gyrase subunit A/B(Staphylococcus aureus)
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50572198(CHEMBL4873479)
Affinity DataIC50:  87nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50572198(CHEMBL4873479)
Affinity DataIC50:  50nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase 4 assessed as reduction in decatenation using supercoiled pNO1 plasmid DNA as substrate incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
National Institute Of Chemistry

Curated by ChEMBL
LigandPNGBDBM50572198(CHEMBL4873479)
Affinity DataIC50:  4nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed