BDBM50574225 CHEMBL4850857
SMILES Cc1cc(Br)c(CNc2ncc(C(=O)NCCCN3CCOC3=O)c(NC3CCCC3)n2)cc1Br
InChI Key InChIKey=BPLPIBNWDLPUKP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50574225
TargetPeripheral plasma membrane protein CASK(Homo sapiens (Human))
Goethe University Frankfurt Am Main
Curated by ChEMBL
Goethe University Frankfurt Am Main
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Inhibition of tracer K5 binding to NanoLuc-fused CASK (unknown origin) expressed in HEK293T cells measured after 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
TargetPeripheral plasma membrane protein CASK(Homo sapiens (Human))
Goethe University Frankfurt Am Main
Curated by ChEMBL
Goethe University Frankfurt Am Main
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of tracer K5 binding to NanoLuc-fused CASK (unknown origin) expressed in HEK293T cells measured after 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Goethe University Frankfurt Am Main
Curated by ChEMBL
Goethe University Frankfurt Am Main
Curated by ChEMBL
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of tracer K5 binding to NanoLuc-fused CSNK1E (unknown origin) expressed in HEK293T cells measured after 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Goethe University Frankfurt Am Main
Curated by ChEMBL
Goethe University Frankfurt Am Main
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of tracer K5 binding to NanoLuc-fused MERTK (unknown origin) expressed in HEK293T cells measured after 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Goethe University Frankfurt Am Main
Curated by ChEMBL
Goethe University Frankfurt Am Main
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of tracer K5 binding to NanoLuc-fused AXL (unknown origin) expressed in HEK293T cells measured after 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Goethe University Frankfurt Am Main
Curated by ChEMBL
Goethe University Frankfurt Am Main
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of tracer K5 binding to NanoLuc-fused ABL1 (unknown origin) expressed in HEK293T cells measured after 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
TargetPeripheral plasma membrane protein CASK(Homo sapiens (Human))
Goethe University Frankfurt Am Main
Curated by ChEMBL
Goethe University Frankfurt Am Main
Curated by ChEMBL
Affinity DataKd: 22nMAssay Description:Binding affinity to recombinant N-terminal His-tagged CASK (1 to 337 residues) (unknown origin) expressed in Escherichia coli assessed as dissociatio...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
Goethe University Frankfurt Am Main
Curated by ChEMBL
Goethe University Frankfurt Am Main
Curated by ChEMBL
Affinity DataIC50: 3.79E+3nMAssay Description:Inhibition of tracer K5 binding to NanoLuc-fused TYRO3 (unknown origin) expressed in HEK293T cells measured after 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair