BDBM50574750 CHEMBL4850758

SMILES CC(C)(C)OC(=O)N[C@@H]1CCN(C1)C(c1ccc(cc1)-c1ccncc1)c1cc2OCOc2cc1O

InChI Key InChIKey=UMKHMAZNAYZVDJ-OSMGYRLQSA-N

Data  1 KI  5 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50574750   

TargetLysine-specific demethylase 4D(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50574750(CHEMBL4850758)
Affinity DataKi:  293nMAssay Description:Mixed inhibition of human KDM4D expressed in Escherichia coli BL21(DE3) using H3(1-21)K9me3 peptide and varying concentrations of 2-OG as substrate p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4D(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50574750(CHEMBL4850758)
Affinity DataKd:  36nMAssay Description:Inhibition of human KDM4D expressed in Escherichia coli BL21 (DE3) assessed as equilibrium dissociation constant measured by isothermal titration cal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6A(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50574750(CHEMBL4850758)
Affinity DataIC50:  3.71E+4nMAssay Description:Inhibition of KDM6A (unknown origin) by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50574750(CHEMBL4850758)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of KDM4A (unknown origin) by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50574750(CHEMBL4850758)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of KDM5A (unknown origin) by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4D(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50574750(CHEMBL4850758)
Affinity DataIC50:  23nMAssay Description:Inhibition of human KDM4D expressed in Escherichia coli BL21 (DE3) using biotinylated H3-derived peptide and 2-OG as substrate preincubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 3B(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50574750(CHEMBL4850758)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of KDM3B (unknown origin) by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed