BDBM50575512 CHEMBL4854625

SMILES COc1nc2ccc(OC)cc2n1CCNC(C)=O

InChI Key InChIKey=OSKMTHQTYBZVLY-UHFFFAOYSA-N

Data  2 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50575512   

TargetMelatonin receptor type 1A(Homo sapiens (Human))
Ach�

Curated by ChEMBL
LigandPNGBDBM50575512(CHEMBL4854625)
Affinity DataKi:  1.20nMAssay Description:Displacement of 2-[1251]-iodomelatonin from human MT1 receptor expressed in CHO cells incubated for 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Ach�

Curated by ChEMBL
LigandPNGBDBM50575512(CHEMBL4854625)
Affinity DataKi:  3.10nMAssay Description:Displacement of 2-[1251]-iodomelatonin from human MT2 receptor expressed in CHO cells incubated for 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Ach�

Curated by ChEMBL
LigandPNGBDBM50575512(CHEMBL4854625)
Affinity DataEC50:  0.520nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells assessed as increase in cAMP production incubated at 37 degreeC by fluorometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Ach�

Curated by ChEMBL
LigandPNGBDBM50575512(CHEMBL4854625)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cells assessed as increase in cAMP levels incubated at 28 degreeC by cellular dielectric spec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Ach�

Curated by ChEMBL
LigandPNGBDBM50575512(CHEMBL4854625)
Affinity DataEC50:  0.0420nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cells assessed as increase in forskolin induced cAMP production incubated at 37 degreeC by Hi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed