BDBM50576705 CHEMBL4850364

SMILES CC1COc2c(N3CCN(C)CC3)c(F)cc3c2n1cc(C(=O)NCc1ccc(CNC(=O)CCc2nc(no2)-c2ccncc2)cc1)c3=O

InChI Key InChIKey=KFOUEKATRAGBCH-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50576705   

TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
The University Of Hong Kong

Curated by ChEMBL
LigandPNGBDBM50576705(CHEMBL4850364)
Affinity DataKi:  5.60E+4nMAssay Description:Inhibition of human recombinant SIRT2 assessed as inhibition of substrate deacetylation using Gln-Pro-Lys-Lys- (epsilon acetyl) AMC peptide as substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
The University Of Hong Kong

Curated by ChEMBL
LigandPNGBDBM50576705(CHEMBL4850364)
Affinity DataIC50:  1.93E+5nMAssay Description:Inhibition of human recombinant SIRT2 assessed as inhibition of substrate deacetylation using Gln-Pro-Lys-Lys- (epsilon acetyl) AMC peptide as substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed