BDBM50576714 CHEMBL4858422

SMILES O=C(CNCCOCCOCCOCCNC(=O)C1CC(=O)c2ccccc12)C1CC2CCC1C2

InChI Key InChIKey=YFUAWADBHBOWPY-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50576714   

TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
The University Of Hong Kong

Curated by ChEMBL
LigandPNGBDBM50576714(CHEMBL4858422)
Affinity DataKi:  6.45E+5nMAssay Description:Inhibition of human recombinant SIRT1 assessed as inhibition of substrate deacetylation using Gln-Pro-Lys-Lys- (epsilon acetyl) AMC peptide as substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
The University Of Hong Kong

Curated by ChEMBL
LigandPNGBDBM50576714(CHEMBL4858422)
Affinity DataIC50:  1.04E+6nMAssay Description:Inhibition of human recombinant SIRT1 assessed as inhibition of substrate deacetylation using Gln-Pro-Lys-Lys- (epsilon acetyl) AMC peptide as substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed