BDBM50576988 CHEMBL4862576
SMILES COc1cc(OC)cc(c1)N(CCNC(C)C)c1ccc2ncc(-c3cnn(C)c3)c(=O)n2c1
InChI Key InChIKey=HRSOTZFHFDXFAE-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50576988
Affinity DataIC50: 0.570nMAssay Description:Inhibition of human N-terminal GST fusion tagged FGFR1 cytoplasmic domain (398 to 822 residues) expressed in baculovirus infected Sf21 insect cells i...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human N-terminal GST fusion tagged FGFR2 cytoplasmic domain (399 to 821 end residues) expressed in baculovirus infected Sf21 insect cel...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant human FGFR4 (442 to 755 residues) using poly(Glu, Tyr) 4:1 as substrate at 40 mins in presence of [gamma33P]ATP by radiomet...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human N-terminal GST fusion tagged FGFR3 cytoplasmic domain (460 to 802 end residues) expressed in baculovirus infected Sf21 insect cel...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Sichuan University
Curated by ChEMBL
Sichuan University
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of human N-terminal GST-fusion tagged VEGFR2 cytoplasmic domain (790 to 1356 end residues) expressed in Sf21 insect cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human N-terminal GST fusion tagged FGFR3 cytoplasmic domain (436 to 806 end residues) expressed in baculovirus infected Sf21 insect cel...More data for this Ligand-Target Pair