BDBM50577169 CHEMBL4846921

SMILES CCN1CCN(CC1)c1ccc(Nc2ncc3scc(-c4cccc(NS(C)(=O)=O)c4)c3n2)cc1

InChI Key InChIKey=MQMVBXQAIMTOTQ-UHFFFAOYSA-N

Data  16 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50577169   

TargetFocal adhesion kinase 1(Homo sapiens (Human))
Yonsei University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50577169(CHEMBL4846921)
Affinity DataIC50:  7nMAssay Description:Inhibition of recombinant FAK (unknown origin) by radiometric kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
Yonsei University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50577169(CHEMBL4846921)
Affinity DataIC50:  30nMAssay Description:Inhibition of EphB1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Yonsei University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50577169(CHEMBL4846921)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of DDR1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Yonsei University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50577169(CHEMBL4846921)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Yonsei University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50577169(CHEMBL4846921)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of TYK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Yonsei University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50577169(CHEMBL4846921)
Affinity DataIC50:  9.70nMAssay Description:Inhibition of FAK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Yonsei University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50577169(CHEMBL4846921)
Affinity DataIC50:  14nMAssay Description:Inhibition of CK2alpha1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Yonsei University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50577169(CHEMBL4846921)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of RET (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fes/Fps(Homo sapiens (Human))
Yonsei University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50577169(CHEMBL4846921)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of Fes (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Yonsei University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50577169(CHEMBL4846921)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of Lck (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Yonsei University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50577169(CHEMBL4846921)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Yonsei University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50577169(CHEMBL4846921)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of Src (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Yonsei University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50577169(CHEMBL4846921)
Affinity DataIC50:  22nMAssay Description:Inhibition of ROS (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Yonsei University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50577169(CHEMBL4846921)
Affinity DataIC50:  8.5nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Yonsei University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50577169(CHEMBL4846921)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of Fyn (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Yonsei University College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50577169(CHEMBL4846921)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of human ERG by patch-clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed