BDBM50577233 CHEMBL4874288

SMILES Cn1cc(Cc2cccc(F)c2)c(n1)-c1cc(Cl)nc(N)n1

InChI Key InChIKey=NVFOMYRKSZVYGO-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50577233   

TargetAdenylate cyclase type 10(Homo sapiens (Human))
Tri-Institutional Institutional Therapeutics Discovery Institute

Curated by ChEMBL
LigandPNGBDBM50577233(CHEMBL4874288)
Affinity DataIC50:  225nMAssay Description:Inhibition of human soluble adenylyl cyclase transfected (4-4 clones)in human HEK293 cells assessed as reduction in cAMP levels preincubated for 5 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAdenylate cyclase type 10(Homo sapiens (Human))
Tri-Institutional Institutional Therapeutics Discovery Institute

Curated by ChEMBL
LigandPNGBDBM50577233(CHEMBL4874288)
Affinity DataIC50:  392nMAssay Description:Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB