BDBM50580327 CHEMBL5089880
SMILES OC(=O)c1cnc(SCCCCc2ccccc2)[nH]c1=O
InChI Key InChIKey=MPSRPXNJOFBAEI-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50580327
TargetHypoxia-inducible factor 1-alpha inhibitor(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: 1.92E+4nMAssay Description:Inhibition of human FIH using HLEVVKLLLEAGADVNAQDK-CONH2 as substrate preincubated for 15 mins followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
Affinity DataIC50: 6.40E+4nMAssay Description:Inhibition of human N-terminal His6-tagged KDM2A (M1 to P517 residues) expressed in insect cells using H3K36(Me2) as substrate preincubated for 15 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 6.59E+4nMAssay Description:Inhibition of human N-terminal His6-tagged KDM3B (L882 to S1761 residues) expressed in insect cells using H3K9(Me2) as substrate preincubated for 15 ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.58E+4nMAssay Description:Inhibition of human KDM6B (D1141 to R1641 residues) expressed in Escherichia coli using H3K27(Me3) as substrate preincubated for 15 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of human N-terminal His6-tagged KDM4D (M1 to G373 residues) expressed in Escherichia coli using H3K9(Me3) as substrate preincubated for 15...More data for this Ligand-Target Pair
Affinity DataIC50: 6.82E+4nMAssay Description:Inhibition of human N-terminal His6-tagged KDM5B (L882 to S1761 residues) expressed in insect cells using H3K4(Me3) as substrate preincubated for 15 ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.43E+4nMAssay Description:Inhibition of human N-terminal His6-tagged KDM4A (M1 to L359 residues) expressed in Escherichia coli using H3K9(Me3) as substrate preincubated for 15...More data for this Ligand-Target Pair